SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549

FORM 12b-25

Commission File Number 000-53125

NOTIFICATION OF LATE FILING

(Check One): o Form 10-K o Form 20-F o Form 11-K x Form 10-Q o Form 10-D
  o Form N-SAR                

For Period Ending: March 31, 2010

o   Transition Report on Form 10-K   o   Transition Report on Form 10-Q
o   Transition Report on Form 20-F   o   Transition Report on Form N-SAR
o   Transition Report on Form 11-K    

Read the attached instruction sheet before preparing form. Please print or type.

Nothing in this form shall be construed to imply that the Commission has verified any information contained herein. If the notification relates to a portion of the filing checked above, identify the Item(s) to which the notification relates:

Part I. Registrant Information

Full name of registrant: iBio, Inc.

Former name if applicable:

Address of principal executive office (Street and number): 9 Innovation Way, Suite 100

City, State and Zip Code: Newark, Delaware 19711

Part II. Rule 12b-25(b) and (c)

          If the subject report could not be filed without unreasonable effort or expense and the registrant seeks relief pursuant to Rule 12b-25(b), the following should be completed. (Check appropriate box.)

X

(a) The reasons described in reasonable detail in Part III of this form could not be eliminated without unreasonable effort or expense;
X

(b) The subject annual report, semi-annual report, transition report on Form 10-K, 20-F, 11-K or Form N-SAR, or portion thereof will be filed on or before the 15th calendar day following the prescribed due date; or the subject quarterly report on transition report on Form 10-Q, or portion thereof will be filed on or before the fifth calendar day following the prescribed due date; and
 

(c) The accountant's statement or other exhibit required by Rule 12b-25(c) has been attached is applicable.
 


Part III. Narrative

          State below in reasonable detail the reasons why Form 10-K, 11-K, 20-F, 10-Q, N-SAR or the transition report portion thereof could not be filed within the prescribed time period. (Attached extra sheets if needed.)

The Company's Quarterly Report on Form 10-Q for the fiscal period ended March 31, 2010 cannot be filed within the prescribed time period because the Company is experiencing delays in the collection and compilation of certain information required to be included in the Form 10-Q. The Company's Quarterly Report on Form 10-Q will be filed on or before the fifth calendar day following the prescribed due date.

Part IV. Other Information

(1)        

Name and telephone number of person to contact in regard to this notification
 
Andrew H. Abramowitz (212) 972-8882
(Name) (Area Code) (Telephone Number)

(2)        

Have all other periodic reports required under Section 13 or 15(d) of the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940 during the preceding 12 months or for such shorter period that the registrant was required to file such report(s) been filed? If the answer is no, identify report(s).
    x Yes          o No

(3)        

Is it anticipated that any significant change in results of operations from the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof?
    o Yes           x No
     
  If so: attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reasons why a reasonable estimate of the results cannot be made.

IBIO, INC.
(Name of registrant as specified in charter)

has caused this notification to be signed on its behalf by the undersigned thereunto duly authorized.

Date May 17, 2010   By: /s/ Frederick Larcombe
      Name: Frederick Larcombe
      Title: Chief Financial Officer