Quarterly report pursuant to Section 13 or 15(d)

Significant Transactions (Details)

v3.25.0.1
Significant Transactions (Details)
3 Months Ended 6 Months Ended 12 Months Ended
Jan. 28, 2025
USD ($)
shares
Dec. 31, 2024
USD ($)
Feb. 25, 2024
USD ($)
Dec. 01, 2022
Sep. 16, 2022
USD ($)
shares
Nov. 01, 2021
USD ($)
$ / shares
shares
Aug. 23, 2021
USD ($)
shares
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2024
USD ($)
Sep. 16, 2022
Sep. 16, 2022
lease
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Indefinite-lived intangible assets   $ 5,003,000           $ 5,003,000     $ 5,003,000     $ 5,003,000    
Accrued licensing fee payable   1,835,000           1,835,000     1,835,000     $ 2,028,000    
General and administrative expenses               2,742,000 $ 2,961,000   5,543,000 $ 6,508,000        
PD-1 Asset Purchase Agreement | Otsuka Pharmaceutical | Intellectual Property                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Proceeds from sale of intellectual property     $ 1,000,000                          
Potential contingent payments related to sale of intellectual property     $ 52,500,000                          
The Purchase and Sale Agreement | College Station Investors                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Purchase price for Ground Lease Property           $ 28,750,000                    
Proceeds from sale of building           28,000,000                    
Base rent expense           $ 151,450                    
Interest rate on lease (percentage of facility's market value)           6.50%                    
The Credit Agreement | Woodforest National Bank                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Principal amount borrowed           $ 22,375,000                    
The Warrant | Bryan Capital | iBio Common Stock                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Warrants, shares issued | shares           2,579                    
Exercise price per share of warrants | $ / shares           $ 665                    
Warrants issued and exercisable | shares           579                    
Value of exercisable warrants           $ 217,255                    
Collaboration, Option and License Agreement | RubrYc Therapeutics                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Collaboration and license agreement, agreement term             5 years                  
Collaboration and license agreement, royalty payment term             10 years                  
AstralBio Exclusive License Agreement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Payment of upfront licensing fee   $ 750,000                            
Notice period to cancel licensing agreement   45 days                            
Notice period to cancel licensing agreement (material breach of contract)   90 days                            
Indefinite-lived intangible assets   $ 750,000           750,000     750,000          
Accrued licensing fee payable   $ 750,000           $ 750,000     $ 750,000          
AstralBio Exclusive License Agreement | Subsequent Events                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Payment of upfront licensing fee $ 750,000                              
Aggregate potential milestone payments payable in licensing agreement $ 28,000,000                              
Equity ownership (ceiling) 19.90%                              
Number of shares issued per agreement | shares 246,087                              
Stock Purchase Agreement | RubrYc Therapeutics | Series A-2 Preferred Stock                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Shares purchased in transaction | shares             2,864,345                  
Value of shares purchased in transaction             $ 7,500,000                  
Asset Purchase Agreement | RubrYc Therapeutics                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Liability for contingent consideration         $ 5,000,000                      
Cash advances to RubrYc to support operations         484,000                      
Transaction costs         208,000                      
Impairment of investment in RubrYc                         $ 1,760,000      
Impairment of current prepaid expense                         288,000      
Impairment of noncurrent prepaid expense                         $ 864,000      
Number of equipment leases assumed in asset acquisition                             3 3
Financing lease liabilities assumed in acquisition         $ 814,000                      
Asset Purchase Agreement | RubrYc Therapeutics | iBio Common Stock                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Number of shares issued per agreement | shares         5,117                      
Fair value of shares issued in agreement         $ 1,000,000                      
Fair value of shares issued and subject to lockup period         $ 650,000                      
Separation Agreement and General Release | Mr. Thomas F. Isett, Former Chief Executive Officer                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Period of bi-monthly installments of current base salary       24 months                        
Period of bi-monthly installments of target bonus       24 months                        
General and administrative expenses                   $ 2,130,000